triple whammy

/T R IH1 P AH0 L W AE0 M IY0/
noun
  1. 1

    (informal) A threefold blow or setback.

  2. 2

    (medicine, informal) An ACE inhibitor or angiotensin receptor blocker, combined with a diuretic and a non-steroidal anti-inflammatory drug, the concurrent use of which may precipitate acute renal failure.

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